Alho A, Strømsøe K, Høiseth A
Orthopaedic Department, Ullevaal Hospital, Oslo, Norway.
Arch Orthop Trauma Surg. 1995;114(4):211-4. doi: 10.1007/BF00444265.
To analyze the mechanical properties of cortical and cancellous bone in the femur and relate them to bone mineral, we retrieved 14 pairs of femurs from elderly subjects at autopsy. Bone mineral was measured by quantitative single-energy computed tomography. Significant associations were found between two types of cortical bone mechanical tests, three-point bending and pull-out of screw, one performed on the right and the other on the left femur. Similarly, pairwise associations were found between the mechanical tests of cancellous bone, punch and cube compression, one performed on the right and the other on the left femur. Also, all mechanical tests correlated with bone mineral as determined by quantitative single-energy computed tomography. In general, bone mass measures correlated better with bone strength than did bone density measures. However, the cortical and cancellous bone mechanical properties were not interrelated, which suggests a separate regulation of the strength of these two types of bone. Bone mineral may not only have importance for the occurrence of fractures; it should be considered as an important factor in the fixation of fragile bone.
为了分析股骨皮质骨和松质骨的力学性能并将其与骨矿物质相关联，我们从老年受试者尸检中获取了14对股骨。通过定量单能计算机断层扫描测量骨矿物质。在两种皮质骨力学测试（三点弯曲和螺钉拔出，一种在右侧股骨进行，另一种在左侧股骨进行）之间发现了显著关联。同样，在松质骨力学测试（冲孔和立方体压缩，一种在右侧股骨进行，另一种在左侧股骨进行）之间也发现了成对关联。此外，所有力学测试都与通过定量单能计算机断层扫描测定的骨矿物质相关。总体而言，骨量测量与骨强度的相关性优于骨密度测量。然而，皮质骨和松质骨的力学性能并不相互关联，这表明这两种类型骨的强度存在独立调节。骨矿物质可能不仅对骨折的发生很重要；它应被视为脆弱骨固定的一个重要因素。
