Syrenskiĭ A V, Tsyrlin V A
Eksp Klin Farmakol. 1995 May-Jun;58(3):23-4.
Experiments in anesthesized cats have shown that the two non-selective beta-adrenergic blocking drugs anapriline (propranolol) and tobanum (cloranolol hydrochloride) enhance vasodilation caused by increasing the blood flow volumetric velocity through the vascular region. It is suggested that the cause of increased vascular bed distensibility induced by these compounds is their capacity to release endothelium-relaxing factor. The cardiac selective beta-adrenoblocker metoprolol tartate had no effects on the regulation of vascular tone.
在麻醉猫身上进行的实验表明，两种非选择性β-肾上腺素能阻断药物心得安（普萘洛尔）和氯甲苯心安（盐酸氯甲苯心安）通过增加血管区域的血流容积速度来增强血管舒张。有人认为，这些化合物引起血管床扩张性增加的原因是它们释放内皮舒张因子的能力。心脏选择性β-肾上腺素能阻滞剂酒石酸美托洛尔对血管张力的调节没有影响。
