1H and 13C NMR study of the molecular interaction mechanism between chloramphenicol and human serum albumin.
作者信息
Panov V, Shipanova I, Michtchenko A, Shabunin I, Shimanovskii N, Sibeldina L, Sergeev P
机构信息
Institute of Chemical Physics RAS, Moscow, Russia.
出版信息
Biochem Mol Biol Int. 1995 Feb;35(2):457-60.
PMID:7663402
Abstract
Molecular mechanism of the interaction between human serum albumin and cloramphenicol was studied by 1H and 13C NMR-spectroscopy. It was found that the main role belongs to [formula: see text] groups of chloramphenicol. A schematic model of the complex-formation between serum albumin and chloramphenicol was proposed.
摘要
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