Tu Y P, Xiao L, Su X F, Yang F Y
National Laboratory of Biomacromolecules, Academia Sinica, Beijing, China.
Biochem Mol Biol Int. 1995 Jun;36(2):383-91.
The effect of Ca2+ on the glucose transporter of human erythrocytes was investigated. The results showed that extracellular Ca2+ had no effect. But, the glucose transport of erythrocytes was markedly inhibited due to the increase in cytoplasmic Ca2+ concentration by addition of ionophore A23187. The Ca2+ inhibition exhibited a dose-dependent manner with an apparent half maximal concentration of 250 microM and could not be recovered by 10 mM EGTA. Unlike Ca2+, Mg2+ did not affect the glucose transporter.
