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[普通变形杆菌感染小鼠肝脏、肾脏和心脏组织中脂质代谢的损伤]

[Impairments of lipid metabolism in liver, kidney and heart tissues of mice infected with Proteus vulgaris].

作者信息

Orlova L G, Gurevitch E I

出版信息

Vopr Med Khim. 1975 Nov-Dec;21(6):613-7.

PMID:766398
Abstract

Intraperitoneal administration of Proteus vulgaris living culture of various age (12 hrs and one day) caused impairments in lipid metabolism in mice liver, kidney and heart tissues. The one day-old culture was more toxic. The impairment in lipid metabolism was manifested as distinct increase in cholesterol content in liver tissue and kidney and a decrease in phospholipid content in liver, kidney and heart tissues. These changes were accompanied by an increase in content of sialic acids in liver tissue.

摘要

腹腔注射不同菌龄(12小时和一天)的普通变形杆菌活培养物会导致小鼠肝脏、肾脏和心脏组织的脂质代谢受损。一天菌龄的培养物毒性更强。脂质代谢受损表现为肝脏组织和肾脏中胆固醇含量明显增加,肝脏、肾脏和心脏组织中磷脂含量降低。这些变化伴随着肝脏组织中唾液酸含量的增加。

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