Shike T, Hoshino H, Takagi M, Inafuku T, Takagi Y
Department of Neurology, Tokyo Saiseikai Central Hospital.
Rinsho Shinkeigaku. 1995 May;35(5):531-6.
A 55-year-old man was admitted with complaints of headache, diplopia, fever and swelling of the right eyelid. Physical examination revealed low grade fever of 37.6 degrees C, but no evidence of infectious focus was detected. The neurological examination disclosed right abducens nerve palsy. An initial routine blood count showed an increased white blood cell count of 11,800/microliters. The erythrocyte sedimentation rate was 93mm and the C-reactive protein level was 3.6mg/dl. Massive epistaxis and hypovolemic shock developed on the 14th day while the patient was receiving antibiotics (CEZ, CMZ) for a possible intracranial infection. The magnetic resonance angiography of the brain and the cerebral angiography demonstrated an aneurysm within the cavernous sinus, which had not been present on the admission. Since epistaxis was caused by a rupture of the aneurysm, internal carotid artery ligation was done. The signs of inflammation improved as well as patients' symptoms. The improvement while using antibiotics strongly implies that the aneurysm was a result of bacterial infection of the cavernous sinus. There have been no reports of ruptured bacterial intracavernous aneurysms presented with massive epistaxis as this case.
一名55岁男性因头痛、复视、发热及右侧眼睑肿胀入院。体格检查发现体温为37.6℃的低热,但未发现感染灶迹象。神经系统检查发现右侧展神经麻痹。初次血常规显示白细胞计数升高至11,800/微升。红细胞沉降率为93mm,C反应蛋白水平为3.6mg/dl。在患者因可能的颅内感染接受抗生素(头孢唑啉、头孢孟多)治疗的第14天,出现大量鼻出血和低血容量性休克。脑部磁共振血管造影和脑血管造影显示海绵窦内有一个动脉瘤,入院时并不存在。由于鼻出血是由动脉瘤破裂引起的,遂进行了颈内动脉结扎术。炎症体征及患者症状均有所改善。使用抗生素期间的病情改善强烈提示该动脉瘤是海绵窦细菌感染的结果。尚无像本病例这样以大量鼻出血为表现的细菌性海绵窦内动脉瘤破裂的报道。