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[结肠癌手术治疗的术后并发症及死亡情况。德国结直肠癌研究组多中心研究结果]

[Postoperative complications and fatalities in surgical therapy of colon carcinoma. Results of the German multicenter study by the Colorectal Carcinoma Study Group].

作者信息

Riedl S, Wiebelt H, Bergmann U, Hermanek P

机构信息

Chirurgische Universitätsklinik Heidelberg.

出版信息

Chirurg. 1995 Jun;66(6):597-606.

PMID:7664589
Abstract

In a prospective multicenter study an analysis of postoperative morbidity and mortality of 1224 patients with colon carcinoma treated in 7 departments of surgery was performed. The postoperative morbidity rate was 23.2% in elective surgery and 39.1% in emergency surgery. Postoperative mortality was 3.4% in elective cases and 11.6% in emergency cases. Preoperative associated diseases, which are more frequent in higher age, advanced tumor stage, and postoperative non-surgical complications rise operative mortality. However, surgical complications increase postoperative mortality only in cases of anastomotic leaks. The rates of postoperative complications depended on different surgical departments. Departments performing a delayed tumor resection in emergency surgery had better results. In elective cases the standard of oncological resections should be observed. In emergency cases operative procedure and extension of the resection should be planed in consideration of preoperative risk factors of the individual patient.

摘要

在一项前瞻性多中心研究中,对7个外科科室治疗的1224例结肠癌患者的术后发病率和死亡率进行了分析。择期手术的术后发病率为23.2%,急诊手术为39.1%。择期病例的术后死亡率为3.4%,急诊病例为11.6%。术前合并症在高龄、肿瘤晚期患者中更为常见,术后非手术并发症会增加手术死亡率。然而,手术并发症仅在吻合口漏的情况下会增加术后死亡率。术后并发症的发生率取决于不同的外科科室。在急诊手术中进行延迟肿瘤切除的科室效果更好。在择期病例中,应遵循肿瘤切除的标准。在急诊病例中,应根据个体患者的术前风险因素规划手术操作和切除范围。

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1
[Postoperative complications and fatalities in surgical therapy of colon carcinoma. Results of the German multicenter study by the Colorectal Carcinoma Study Group].[结肠癌手术治疗的术后并发症及死亡情况。德国结直肠癌研究组多中心研究结果]
Chirurg. 1995 Jun;66(6):597-606.
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[Oncologic surgery in advanced age: results in colorectal carcinoma].高龄患者的肿瘤外科手术:结直肠癌手术结果
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:499-501.
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[Radical resection of colorectal carcinoma in the oldest old].[老年直肠癌的根治性切除术]
Chirurg. 2002 Mar;73(3):241-4. doi: 10.1007/s00104-001-0381-5.
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[Results of multivisceral resection of primary colorectal cancer].[原发性结直肠癌多脏器切除的结果]
Zentralbl Chir. 2006 Jun;131(3):217-22. doi: 10.1055/s-2006-933467.
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[Risk factors of perioperative morbidity and mortality in colorectal cancer with special reference to tumor stage, site and age].[结直肠癌围手术期发病和死亡的危险因素,特别涉及肿瘤分期、部位和年龄]
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Surgery of colorectal carcinoma in patients aged over 80.80岁以上患者的结直肠癌手术
Onkologie. 2009 Feb;32(1-2):10-6. doi: 10.1159/000184580. Epub 2009 Jan 20.
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[Extensive surgery of colorectal carcinoma in the elderly--a justified therapy approach].老年人大肠癌的广泛手术——一种合理的治疗方法
Langenbecks Arch Chir Suppl Kongressbd. 1996;113:502-4.
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["Colon-/rectal carcinoma" prospective studies as comprehensive surgical quality assurance].["结肠癌/直肠癌”前瞻性研究作为全面的外科手术质量保证]
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Postoperative mortality and morbidity in French patients undergoing colorectal surgery: results of a prospective multicenter study.法国接受结直肠手术患者的术后死亡率和发病率:一项前瞻性多中心研究的结果
Arch Surg. 2005 Mar;140(3):278-83, discussion 284. doi: 10.1001/archsurg.140.3.278.

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