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[结直肠癌围手术期发病和死亡的危险因素,特别涉及肿瘤分期、部位和年龄]

[Risk factors of perioperative morbidity and mortality in colorectal cancer with special reference to tumor stage, site and age].

作者信息

Menke H, Graf J M, Heintz A, Klein A, Junginger T

机构信息

Klinik für Allgemein und Abdominalchirurgie, Johannes Gutenberg Universität Mainz.

出版信息

Zentralbl Chir. 1993;118(1):40-6.

PMID:8451887
Abstract

The perioperative risk was prospectively analyzed in 511 patients with colorectal cancer, out of which 5% had an emergency procedure. The morbidity rate was 23.6% without an association with tumour stage or localization. The incidence of nonsurgical complications rose with increasing age because of a rising number of concomitant illnesses (< 50: 5.7%, > 80: 28.1%). The morbidity was associated with an increasing blood loss during the operation (< 500 ml: 10.6%, > 2000 ml: 30.4%), but not with the type of treatment. The overall operative mortality rate was 2.3% with the same rate of surgical complications and complications of preexisting conditions. Morbidity and mortality following emergency procedure were 56%, respectively 20%, expressing mainly septical complications of colorectal cancer.

摘要

对511例结直肠癌患者的围手术期风险进行了前瞻性分析,其中5%接受了急诊手术。发病率为23.6%,与肿瘤分期或部位无关。由于伴随疾病数量增加,非手术并发症的发生率随年龄增长而上升(<50岁:5.7%,>80岁:28.1%)。发病率与手术期间出血量增加有关(<500毫升:10.6%,>2000毫升:30.4%),但与治疗类型无关。总体手术死亡率为2.3%,手术并发症和原有疾病并发症的发生率相同。急诊手术后的发病率和死亡率分别为56%和20%,主要表现为结直肠癌的感染性并发症。

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