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[结直肠癌围手术期发病和死亡的危险因素,特别涉及肿瘤分期、部位和年龄]

[Risk factors of perioperative morbidity and mortality in colorectal cancer with special reference to tumor stage, site and age].

作者信息

Menke H, Graf J M, Heintz A, Klein A, Junginger T

机构信息

Klinik für Allgemein und Abdominalchirurgie, Johannes Gutenberg Universität Mainz.

出版信息

Zentralbl Chir. 1993;118(1):40-6.

PMID:8451887
Abstract

The perioperative risk was prospectively analyzed in 511 patients with colorectal cancer, out of which 5% had an emergency procedure. The morbidity rate was 23.6% without an association with tumour stage or localization. The incidence of nonsurgical complications rose with increasing age because of a rising number of concomitant illnesses (< 50: 5.7%, > 80: 28.1%). The morbidity was associated with an increasing blood loss during the operation (< 500 ml: 10.6%, > 2000 ml: 30.4%), but not with the type of treatment. The overall operative mortality rate was 2.3% with the same rate of surgical complications and complications of preexisting conditions. Morbidity and mortality following emergency procedure were 56%, respectively 20%, expressing mainly septical complications of colorectal cancer.

摘要

对511例结直肠癌患者的围手术期风险进行了前瞻性分析,其中5%接受了急诊手术。发病率为23.6%,与肿瘤分期或部位无关。由于伴随疾病数量增加,非手术并发症的发生率随年龄增长而上升(<50岁:5.7%,>80岁:28.1%)。发病率与手术期间出血量增加有关(<500毫升:10.6%,>2000毫升:30.4%),但与治疗类型无关。总体手术死亡率为2.3%,手术并发症和原有疾病并发症的发生率相同。急诊手术后的发病率和死亡率分别为56%和20%,主要表现为结直肠癌的感染性并发症。

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1
[Risk factors of perioperative morbidity and mortality in colorectal cancer with special reference to tumor stage, site and age].[结直肠癌围手术期发病和死亡的危险因素,特别涉及肿瘤分期、部位和年龄]
Zentralbl Chir. 1993;118(1):40-6.
2
[Postoperative complications and fatalities in surgical therapy of colon carcinoma. Results of the German multicenter study by the Colorectal Carcinoma Study Group].[结肠癌手术治疗的术后并发症及死亡情况。德国结直肠癌研究组多中心研究结果]
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[Colorectal cancer surgery. Analysis of risk factors in relation to incidence of morbidity and mortality].[结直肠癌手术。与发病率和死亡率相关的危险因素分析]
Chir Ital. 2006 Nov-Dec;58(6):723-32.
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Presentation, treatment, and multivariate analysis of risk factors for obstructive and perforative colorectal carcinoma.梗阻性和穿孔性结直肠癌的临床表现、治疗及危险因素的多变量分析
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Audit of definitive colorectal surgery in patients with early and advanced colorectal cancer.早期和晚期结直肠癌患者确定性结直肠手术的审计
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Colorectal cancer among patients aged 75 years or over.75岁及以上患者中的结直肠癌
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Colorectal carcinoma in patients aged 75 years and more: factors influencing short and long-term operative mortality.75岁及以上患者的结直肠癌:影响短期和长期手术死亡率的因素
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Risk factors and operative mortality in surgery for colorectal cancer.结直肠癌手术的危险因素与手术死亡率
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Postoperative mortality and morbidity in French patients undergoing colorectal surgery: results of a prospective multicenter study.法国接受结直肠手术患者的术后死亡率和发病率:一项前瞻性多中心研究的结果
Arch Surg. 2005 Mar;140(3):278-83, discussion 284. doi: 10.1001/archsurg.140.3.278.

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Int J Colorectal Dis. 2007 Dec;22(12):1469-74. doi: 10.1007/s00384-007-0317-8. Epub 2007 May 5.
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The impact of age on post-operative outcomes of colorectal cancer patients undergoing surgical treatment.年龄对接受手术治疗的结直肠癌患者术后结局的影响。
BMC Cancer. 2005 Dec 2;5:153. doi: 10.1186/1471-2407-5-153.
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The impact of the risk factor "age" on the early postoperative results of surgery for colorectal carcinoma and its significance for perioperative management.风险因素“年龄”对结直肠癌手术早期术后结果的影响及其对围手术期管理的意义。
World J Surg. 2005 Aug;29(8):1013-21; discussion 1021-2. doi: 10.1007/s00268-005-7711-6.