Chalut C, Gallois Y, Poterszman A, Moncollin V, Egly J M
Institute de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, C.U. de Strasbourg, France.
Gene. 1995 Aug 19;161(2):277-82. doi: 10.1016/0378-1119(95)00209-o.
The gene encoding the human TATA-box-binding protein (hTBP) is contained within a 20-kb DNA fragment and is split into eight exons. The coding sequence is interrupted by six introns and the 5'-untranslated region (5'-UTR) of the gene by a 2.5-kb intron. A comparison of the hTBP exon/intron organization with the various TBP cloned to date is presented.