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Genomic structure of the human TATA-box-binding protein (TBP).

作者信息

Chalut C, Gallois Y, Poterszman A, Moncollin V, Egly J M

机构信息

Institute de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, C.U. de Strasbourg, France.

出版信息

Gene. 1995 Aug 19;161(2):277-82. doi: 10.1016/0378-1119(95)00209-o.

Abstract

The gene encoding the human TATA-box-binding protein (hTBP) is contained within a 20-kb DNA fragment and is split into eight exons. The coding sequence is interrupted by six introns and the 5'-untranslated region (5'-UTR) of the gene by a 2.5-kb intron. A comparison of the hTBP exon/intron organization with the various TBP cloned to date is presented.

摘要

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