沙眼衣原体的甘氨酰-tRNA合成酶。
The glycyl-tRNA synthetase of Chlamydia trachomatis.
作者信息
Wagar E A, Giese M J, Yasin B, Pang M
机构信息
Department of Pathology, UCLA School of Medicine 90095, USA.
出版信息
J Bacteriol. 1995 Sep;177(17):5179-85. doi: 10.1128/jb.177.17.5179-5185.1995.
Abstract
Aminoacyl-tRNA synthetases specifically charge tRNAs with their cognate amino acids. A prototype for the most complex aminoacyl-tRNA synthetases is the four-subunit glycyl-tRNA synthetase from Escherichia coli, encoded by two open reading frames. We examined the glycyl-tRNA synthetase gene from Chlamydia trachomatis, a genetically isolated bacterium, and identified only a single open reading frame for the chlamydial homolog (glyQS). This is the first report of a prokaryotic glycyl-tRNA synthetase encoded by a single gene.
摘要
氨酰-tRNA合成酶特异性地将其对应的氨基酸加载到tRNA上。最复杂的氨酰-tRNA合成酶的一个原型是来自大肠杆菌的由两个开放阅读框编码的四亚基甘氨酰-tRNA合成酶。我们研究了沙眼衣原体（一种基因上孤立的细菌）的甘氨酰-tRNA合成酶基因，并确定衣原体同源物（glyQS）只有一个开放阅读框。这是关于由单个基因编码的原核甘氨酰-tRNA合成酶的首次报道。
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本文引用的文献
1
Crystallisation of trypsin-modified methionyl-tRNA synthetase from Escherichia coli.
FEBS Lett. 1971 Aug 15;16(3):186-188. doi: 10.1016/0014-5793(71)80128-x.
2
Identification of an early-stage gene of Chlamydia psittaci 6BC.鹦鹉热衣原体6BC早期基因的鉴定
J Bacteriol. 1993 May;175(10):2936-42. doi: 10.1128/jb.175.10.2936-2942.1993.
3
Primary structure of the gene for glycyl-tRNA synthetase from Bombyx mori.家蚕甘氨酰 - tRNA合成酶基因的一级结构。
J Biol Chem. 1993 Apr 15;268(11):7660-7.
4
tRNA structure and aminoacylation efficiency.转运RNA的结构与氨酰化效率
Prog Nucleic Acid Res Mol Biol. 1993;45:129-206. doi: 10.1016/s0079-6603(08)60869-7.
5
6
Primary structure and functional expression of human Glycyl-tRNA synthetase, an autoantigen in myositis.
J Biol Chem. 1994 Nov 18;269(46):28790-7.
7
Functions of the gene products of Escherichia coli.大肠杆菌基因产物的功能。
Microbiol Rev. 1993 Dec;57(4):862-952. doi: 10.1128/mr.57.4.862-952.1993.
8
The transfer RNA identity problem: a search for rules.转运RNA识别问题：规则探寻
Science. 1994 Jan 14;263(5144):191-7. doi: 10.1126/science.7506844.
9
Purification and properties of alanine tRNA synthetase from Escherichia coli A tetramer of identical subunits.来自大肠杆菌的丙氨酸tRNA合成酶的纯化及特性 一种由相同亚基组成的四聚体。
J Biol Chem. 1981 Jan 10;256(1):198-204.
10
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding.通过定点诱变重新设计酶结构：酪氨酰tRNA合成酶与ATP结合
Nature. 1982 Oct 21;299(5885):756-8. doi: 10.1038/299756a0.
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