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温度及热休克对大肠杆菌素A裂解蛋白表达及作用的影响

Effects of temperature and of heat shock on the expression and action of the colicin A lysis protein.

作者信息

Cavard D

机构信息

Laboratoire d'Ingénierie et de Dynamique des Systèmes Membranaires, Centre National de la Recherche Scientifique, Marseille, France.

出版信息

J Bacteriol. 1995 Sep;177(17):5189-92. doi: 10.1128/jb.177.17.5189-5192.1995.

DOI:10.1128/jb.177.17.5189-5192.1995
PMID:7665505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC177306/
Abstract

At low temperature, the synthesis of the colicin A lysis protein in Escherichia coli was slowed down, and consequently its functioning was retarded. The rates were restored when the bacteria were shifted for 10 min to 42 degrees C, except in an rpoH mutant, suggesting that one or more proteins regulated by sigma 32 is necessary for expression of colicin A lysis protein.

摘要

在低温下,大肠杆菌中大肠杆菌素A裂解蛋白的合成速度减慢,其功能也因此受到抑制。当细菌转移至42℃ 10分钟后,合成速度恢复正常,但rpoH突变体除外,这表明σ32调控的一种或多种蛋白质对于大肠杆菌素A裂解蛋白的表达是必需的。

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本文引用的文献

1
Escherichia coli SecB, SecA, and SecY proteins are required for expression and membrane insertion of the bacteriocin release protein, a small lipoprotein.大肠杆菌的SecB、SecA和SecY蛋白是细菌素释放蛋白(一种小脂蛋白)表达和膜插入所必需的。
J Bacteriol. 1993 Mar;175(5):1543-7. doi: 10.1128/jb.175.5.1543-1547.1993.
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Accumulation of secretory protein precursors in Escherichia coli induces the heat shock response.大肠杆菌中分泌蛋白前体的积累会诱导热休克反应。
J Bacteriol. 1993 Jul;175(13):3992-7. doi: 10.1128/jb.175.13.3992-3997.1993.
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Molecular characterization of enterobacterial pldA genes encoding outer membrane phospholipase A.编码外膜磷脂酶A的肠杆菌属pldA基因的分子特征分析
J Bacteriol. 1994 Feb;176(3):861-70. doi: 10.1128/jb.176.3.861-870.1994.
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Truncated mutants of the colicin A lysis protein are acylated and processed when overproduced.
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Colicin E2 release: lysis, leakage or secretion? Possible role of a phospholipase.大肠杆菌素E2的释放:裂解、渗漏还是分泌?磷脂酶的可能作用。
EMBO J. 1984 Oct;3(10):2393-7. doi: 10.1002/j.1460-2075.1984.tb02145.x.
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The htpR gene product of E. coli is a sigma factor for heat-shock promoters.大肠杆菌的htpR基因产物是热休克启动子的一种σ因子。
Cell. 1984 Sep;38(2):383-90. doi: 10.1016/0092-8674(84)90493-8.
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Isolation and physical mapping of temperature-sensitive mutants defective in heat-shock induction of proteins in Escherichia coli.大肠杆菌中热休克诱导蛋白缺陷的温度敏感突变体的分离与物理图谱分析。
Mol Gen Genet. 1984;195(1-2):10-6. doi: 10.1007/BF00332716.
8
Extracellular release of colicin A is non-specific.大肠杆菌素A的细胞外释放是非特异性的。
EMBO J. 1987 Aug;6(8):2463-8. doi: 10.1002/j.1460-2075.1987.tb02526.x.
9
Temporal control of colicin E1 induction.大肠杆菌素E1诱导的时间控制
J Bacteriol. 1987 Nov;169(11):5028-34. doi: 10.1128/jb.169.11.5028-5034.1987.
10
The acylated precursor form of the colicin A lysis protein is a natural substrate of the DegP protease.大肠杆菌素A裂解蛋白的酰化前体形式是DegP蛋白酶的天然底物。
J Bacteriol. 1989 Nov;171(11):6316-22. doi: 10.1128/jb.171.11.6316-6322.1989.