Attia R A, Rizk H, Motawea S
Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
J Egypt Soc Parasitol. 1995 Aug;25(2):485-90.
This study is composed of a community based study and a hospital based study. The community based study was conducted on 200 apparently healthy individuals randomly chosen from rural areas. They were examined clinically, sonographically and parasitologically for E. histolytica cysts and by ELISA for circulating amoebic antigen. They were negative for antigenaemia at 1/16 which was considered the diagnostic titre of amoebic hepatitis. The hospital based study was carried out on 27 patients suffering from amoebic liver abscess (ALA). Circulating amoebic antigen was detected in 66.66% of them before treatment which decreased to 14.82% two months after treatment. There was no significant association between the diameter of the abscess and the level of circulating amoebic antigen. It was concluded that the circulating amoebic antigen may be useful for the diagnosis and follow up of amoebic liver abscess patients.
本研究由一项基于社区的研究和一项基于医院的研究组成。基于社区的研究在从农村地区随机选取的200名明显健康的个体中进行。对他们进行了临床、超声和寄生虫学检查以检测溶组织内阿米巴囊肿，并通过酶联免疫吸附测定法检测循环阿米巴抗原。他们的抗原血症在1/16时为阴性，这被认为是阿米巴肝炎的诊断滴度。基于医院的研究在27例患有阿米巴肝脓肿（ALA）的患者中开展。治疗前，66.66%的患者检测到循环阿米巴抗原，治疗两个月后该比例降至14.82%。脓肿直径与循环阿米巴抗原水平之间无显著关联。得出的结论是，循环阿米巴抗原可能对阿米巴肝脓肿患者的诊断和随访有用。
