Lommatzsch P
Am J Ophthalmol. 1976 Feb;81(2):198-206. doi: 10.1016/0002-9394(76)90731-5.
Fifteen patients with malignant epithelial tumors of the conjunctiva were treated with beta-ray ocular applicators filled with radioactive strontium and yttrium (90Sr/90Y). Histologic examination confirmed the diagnosis. There were ten squamous cell carcinomas, four carcinomas in situ, and one case of epidermidalization. In one patient, who may have received an insufficient dose, recurrence led to enucleation. Radiogenic complications-secondary glaucoma and corneal degeneration-caused visual loss in two other patients. All of the other tumors disappeared completely without seriously affecting the eyes. Beta-ray irradiation with 90Sr/90Y applicators was effective if a sufficient dose (15,000 to 18,000 rads) was applied to the tumor surface and if the height of the tumor did not exceed 5 mm.
15例结膜恶性上皮肿瘤患者接受了填充有放射性锶和钇（90Sr/90Y）的β射线眼部敷贴器治疗。组织学检查确诊。其中有10例鳞状细胞癌、4例原位癌和1例表皮化生。1例患者可能接受的剂量不足，复发后导致眼球摘除。放射性并发症——继发性青光眼和角膜变性——导致另外2例患者视力丧失。所有其他肿瘤完全消失，未对眼睛造成严重影响。如果向肿瘤表面施加足够剂量（15,000至18,000拉德）且肿瘤高度不超过5毫米，使用90Sr/90Y敷贴器进行β射线照射是有效的。
