Mori Y, Kobayashi T, Shibata T, Satake T
Department of Neurosurgery, Nagoya University School of Medicine.
No Shinkei Geka. 1995 Aug;23(8):745-9.
A case of intracranial dural malignant lymphoma was presented. A 35-year-old woman was admitted with generalized seizure. The neurological findings and laboratory data were normal. Computed tomography (CT) showed a nodular lesion in the left frontal convexity with marked enhancement by contrast medium. Angiography showed a slight tumor stain and the feeding artery from the ethmoid artery. On surgery, a soft pinkish tumor was found to be located in the dura and subdural space. It was resected subtotally. The histological diagnosis was malignant lymphoma of B cell origin. Postoperative Ga scintigraphy and abdominal CT disclosed no abnormalities in other organs, but bone marrow examination revealed lymphoma cells, which suggested that the patient might have systemic lymphoma. The patient and her family refused additional treatment. The patient is alive and well now over six years after the craniotomy. Primary central nervous system (CNS) lymphomas usually arise in the cerebral parenchyma, while secondary CNS lymphomas commonly involve leptomeninges and perivascular spaces. Mass lesions arising in the dura are very rare.
本文报告一例颅内硬脑膜恶性淋巴瘤。一名35岁女性因全身性癫痫发作入院。神经系统检查结果和实验室数据均正常。计算机断层扫描（CT）显示左额部凸面有一个结节性病变，造影剂增强明显。血管造影显示有轻微的肿瘤染色，供血动脉来自筛动脉。手术中发现一个粉红色软肿瘤位于硬脑膜和硬膜下间隙。肿瘤被部分切除。组织学诊断为B细胞起源的恶性淋巴瘤。术后镓闪烁显像和腹部CT显示其他器官无异常，但骨髓检查发现淋巴瘤细胞，提示患者可能患有全身性淋巴瘤。患者及其家属拒绝进一步治疗。开颅手术后六年多，患者目前仍健在且状况良好。原发性中枢神经系统（CNS）淋巴瘤通常发生在脑实质，而继发性CNS淋巴瘤通常累及软脑膜和血管周围间隙。起源于硬脑膜的肿块病变非常罕见。
