Section of Neurosurgery, MC 3026, The University of Chicago Hospital, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA.
J Clin Neurosci. 2010 May;17(5):666-9. doi: 10.1016/j.jocn.2009.10.001. Epub 2010 Mar 3.
Primary central nervous system lymphomas are a rare lymphoid tumor. A small proportion of these lymphomas are low-grade B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) subgroup. A primary MALT-lymphoma of the dura is very rare, with only a few reports. These low-grade tumors respond favorably to a combination of surgery and post-operative regional external beam radiotherapy. Differentiating these lesions from primary lymphomas or other dural-based lesions is therefore critical to determine clinical management and future prognosis. We report a 29-year-old patient with visual loss and dural-based MALT lymphoma and discuss the pertinent findings as well as the clinical management of patients with this unusual lesion.
原发性中枢神经系统淋巴瘤是一种罕见的淋巴肿瘤。其中一小部分为黏膜相关淋巴组织（MALT）亚型的低级 B 细胞淋巴瘤。硬脑膜原发性 MALT 淋巴瘤非常罕见，仅有少数报道。这些低级肿瘤对手术联合术后区域性外照射治疗反应良好。因此，区分这些病变与原发性淋巴瘤或其他硬脑膜病变对于确定临床管理和未来预后至关重要。我们报告了一例 29 岁的视觉丧失和硬脑膜 MALT 淋巴瘤患者，并讨论了相关发现以及此类罕见病变患者的临床管理。
