Zahl P H
Section of Medical Statistics, University of Oslo, Norway.
Stat Med. 1995 Jun 15;14(11):1249-61. doi: 10.1002/sim.4780141109.
Twenty year survival of all Norwegians with colon cancer registered in a period of 10 years is estimated by both relative survival rates, and with a proportional regression model for the excess intensity. Male colon cancer patients have a significant positive excess mortality at least 20 years after diagnosis, while the excess mortality for females is about zero after 10 years. Stratified analyses for men indicate non-proportionality throughout the follow-up period, and when this information is included in the regression model, there are significant effects of age between 60 and 70 years and for pelvic cancer. The use of proportional regression models is also discussed when excess intensities are close to zero or negative.
通过相对生存率以及用于超额强度的比例回归模型,对在10年期间登记的所有挪威结肠癌患者的20年生存率进行了估计。男性结肠癌患者在诊断后至少20年有显著的正超额死亡率,而女性的超额死亡率在10年后约为零。对男性的分层分析表明在整个随访期内不成比例,当将此信息纳入回归模型时,60至70岁之间的年龄以及盆腔癌有显著影响。当超额强度接近零或为负时,也讨论了比例回归模型的使用。