Cao W C, Xu J F, Ren Z X
Shandong Institute of Parasitic Diseases, Jining, People's Republic of China.
Southeast Asian J Trop Med Public Health. 1994 Dec;25(4):714-8.
Shandong Province used to be the highly endemic area of Wuchereria bancrofti. Culex pipiens pallens was the main mosquito vector. After about 30 years of large scale anti-filariasis control campaign, filariasis was controlled throughout the province in 1983. Since then, extensive cross-sectional and consecutive longtitudinal surveillances have been carried out. Parasitological and entomological data indicated that the microfilaremia rate of the human population, and the natural infection rate of mosquito vector kept declining, with many villages dropping to zero; no children under ten were infected. Serological surveillance showed that antifilarial antibody had fallen to the same level as that in non-endemic areas 10-15 years after control. In addition, patients with chronic manifestations were reduced in number. It is suggested that the achievement in filariasis control in Shandong Province is stable: the transmission of filariasis has been interrupted. However, there are still a few residual microfilaremia cases, which may bring about new infection under conditions favorable for transmission. Infectious sources may be introduced by population movements from a neighboring province where filariasis is still endemic at present. Moreover, new cases with chronic manifestations, especially chyluria, continually emerge. So systematic surveillance should be continued and proper control measures must be taken to eventually wipe the disease out of the province.
山东省曾是班氏丝虫病的高度流行区。淡色库蚊是主要的蚊媒。经过约30年的大规模防治丝虫病运动，1983年全省丝虫病得到控制。此后，开展了广泛的横断面和连续纵向监测。寄生虫学和昆虫学数据表明，人群微丝蚴血症率和蚊媒自然感染率持续下降，许多村庄降至零；10岁以下儿童无感染。血清学监测显示，防治后10 - 15年，抗丝虫抗体已降至与非流行区相同水平。此外，慢性病例数量减少。提示山东省丝虫病防治成果稳定：丝虫病传播已被阻断。然而，仍有少数残留微丝蚴血症病例，在有利于传播的条件下可能导致新的感染。传染源可能由目前仍有丝虫病流行的邻省人口流动传入。此外，慢性病例尤其是乳糜尿新病例不断出现。因此，应继续进行系统监测并采取适当防治措施，最终在全省消灭该病。
