Sun D J, Chen P L
Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai.
Southeast Asian J Trop Med Public Health. 1992 Sep;23(3):369-76.
From 1956, when filariasis control was first listed in our national program, up to 1991, a cumulative total of 677,931,521 person-time blood examinations and 217,472,045 person-time diethylcarbamazine treatments were made in the whole country, and 835 (96.6%) out of the 864 endemic counties achieved the criterion for control of filariasis. Surveillance data collected in various provinces, autonomous regions and municipalities starting from the second year after they reached the criterion for control of filariasis demonstrated that in 1991 the microfilarial rate in human populations and natural infection of filarial larvae in mosquito vector populations in previous endemic areas had already declined to a very low level, even zero, without resurgence in quite a number of villages. In some places where filariasis was brought under control relatively early, the anti-filarial antibody positive rate of the human population has fallen to a level the same as or similar to that in nonendemic areas. Therefore, the data suggest that in most places where filariasis has been controlled, the transmission of bancroftian filariasis and periodic malayan filariasis has been interrupted. However, filariasis is still endemic in 29 counties in China at present, the danger of introduction of sources of infection by the floating population hasn't been extinguished yet, and there are still a few areas with weak links in filariasis control. Therefore, control work still needs to be strengthened and systematic surveillance must be pursued until the elimination of filariasis in the whole country.
自1956年我国首次将丝虫病防治列入国家计划起,至1991年,全国累计血检677931521人次,服用乙胺嗪217472045人次,864个丝虫病流行县中有835个(96.6%)达到丝虫病防治标准。各省、自治区、直辖市自达到防治标准后的次年起收集的监测资料表明,1991年原流行区人群微丝蚴率及蚊媒丝虫幼虫自然感染率均已降至很低水平,甚至为零,不少村庄未再出现流行。在一些丝虫病控制较早的地方,人群抗丝虫抗体阳性率已降至与非流行区相同或相近的水平。因此,资料提示,我国多数已控制丝虫病流行的地区,班氏丝虫病和马来丝虫病的传播已被阻断。但是,目前我国仍有29个县存在丝虫病流行,流动人口输入传染源的危险尚未消除,丝虫病防治工作仍存在薄弱环节,因此,仍需加强防治工作,继续开展系统监测,直至全国消灭丝虫病。