O'Leary S J, Clark G M, Tong Y C
Department of Otolaryngology, University of Melbourne, Australia.
Ann Otol Rhinol Laryngol Suppl. 1995 Sep;166:124-6.
Discharge rate-level (I/O) functions possessed by dorsal cochlear nucleus (DCN) units were examined, in response to bipolar electrical stimulation of the cochlea of the barbiturate-anesthetized cat. Spontaneously active units usually possessed nonmonotonic functions with a minimum, and spontaneously inactive units usually possessed monotonic functions or nonmonotonic functions with a maximum (NM+). In response to acoustic high-pass filtered noise, the function relating discharge rate and cutoff frequency resembled the same unit's I/O function to electrical stimulation. The I/O functions to acoustic characteristic tones were usually monotonic or NM+. These results suggest that in the DCN, a prerequisite for the generation of acoustic-like responses with an electrical stimulus may be the matching of the cochlear place and spatial extent activated by each stimulus.
研究了在巴比妥麻醉猫的耳蜗受到双极电刺激时，蜗背侧核（DCN）神经元所具有的放电率-电平（输入/输出）功能。自发放电的神经元通常具有带有最小值的非单调功能，而自发无放电的神经元通常具有单调功能或带有最大值的非单调功能（NM+）。对于声学高通滤波噪声，放电率与截止频率之间的函数类似于同一神经元对电刺激的输入/输出功能。对声学特征音调的输入/输出功能通常是单调的或NM+。这些结果表明，在DCN中，用电刺激产生类似声学反应的一个先决条件可能是每个刺激激活的耳蜗部位和空间范围的匹配。
