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一名儿童原发性纵隔血管外皮细胞瘤并导致致命后果

Primary mediastinal hemangiopericytoma with fatal outcome in a child.

作者信息

Simonton S C, Swanson P E, Watterson J, Priest J R

机构信息

Department of Pathology, Children's Health Care-St Paul (Minn) 55102, USA.

出版信息

Arch Pathol Lab Med. 1995 Sep;119(9):839-41.

PMID:7668943
Abstract

Hemangiopericytoma occurs infrequently in children, and mediastinal sites are exceedingly rare. We report a case of mediastinal hemangiopericytoma in a 4-year-old child, which resulted in the patient's death due to large size, anatomic location, and associated perioperative bleeding. The pathologic diagnosis was established on the basis of light microscopic, immunohistochemical, and electron microscopic features. The presentation and clinical course of this case contrast with those of congenital or infantile hemangiopericytoma, which generally has a favorable outcome. Hemangiopericytoma should be considered in the differential diagnosis of large mediastinal masses in children.

摘要

血管外皮细胞瘤在儿童中很少见,纵隔部位极为罕见。我们报告一例4岁儿童纵隔血管外皮细胞瘤,因其体积大、解剖位置及围手术期出血导致患者死亡。病理诊断基于光镜、免疫组化和电镜特征得以确立。该病例的表现和临床过程与先天性或婴儿型血管外皮细胞瘤不同,后者通常预后良好。儿童纵隔大肿块的鉴别诊断应考虑血管外皮细胞瘤。

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