Spagliardi E, Barra M, Orsi D, Torelli P
II Divisione di Chirurgia Generale, XIII USL-GE4, Ospedale San Martino.
G Chir. 1995 Apr;16(4):187-90.
The Authors analyze a series of 441 patients affected by carcinoma of the colon operated on between June 1980 and November 1993. The incidence of the different stages of the disease according to Dukes resulted comparable to that reported in the literature as well as the incidence of morbidity and mortality. Recostruction was performed in all cases with mechanical sutures (T-L for the right colon and L-T for the left colon) and without protection enterostomy. Long-term results evaluated by actuarial methods were influenced by the stage of the disease, and not by sex or duration of symptoms. The need of early diagnosis as well as oncologically correct surgical technique is furthermore confirmed. The importance of clinical trials on adjuvant chemotherapy is emphasized in order to improve survival in patients operated for stage B and C colon cancer.
作者分析了1980年6月至1993年11月间接受结肠癌手术的441例患者。根据Dukes分期,该疾病不同阶段的发病率以及发病率和死亡率与文献报道相当。所有病例均采用机械缝合(右半结肠采用T-L法,左半结肠采用L-T法)且未行保护性肠造口术进行重建。通过精算方法评估的长期结果受疾病阶段影响,而非性别或症状持续时间。此外,进一步证实了早期诊断以及肿瘤学上正确的手术技术的必要性。强调了辅助化疗临床试验的重要性,以提高B期和C期结肠癌手术患者的生存率。