Siddall P, Xu C L, Cousins M
Pain Management and Research Centre, University of Sydney, Royal North Shore Hospital, St Leonards, NSW, Australia.
Neuroreport. 1995 Jun 19;6(9):1241-4. doi: 10.1097/00001756-199506090-00003.
A weight-drop model of spinal cord injury was used to characterize the sensory changes that occur following mechanical trauma to the spinal cord and to determine the relationship of these changes to the extent of lesion. Weight-drop from different heights resulted in significant differences in motor dysfunction between experimental groups. These groups also demonstrated significant differences in the incidence of allodynia (decreased vocalization threshold to mechanical pressure). The incidence of allodynia was higher in the group that had incomplete spinal cord lesions confined to the central and dorsal regions of the spinal cord and lower in the groups that had either more extensive spinal cord damage or no apparent damage.
采用脊髓损伤的重物坠落模型来描述脊髓机械性创伤后发生的感觉变化，并确定这些变化与损伤程度之间的关系。从不同高度坠落重物导致实验组之间运动功能障碍存在显著差异。这些组在异常性疼痛（对机械压力的发声阈值降低）的发生率上也表现出显著差异。在脊髓损伤局限于脊髓中央和背侧区域的不完全损伤组中，异常性疼痛的发生率较高，而在脊髓损伤更广泛或无明显损伤的组中，发生率较低。
