Lauffenburger M D, Dull S T, Toselli R
Division of Neurosurgery, University of North Carolina, Chapel Hill 27599-7060, USA.
J Spinal Disord. 1995 Jun;8(3):243-8. doi: 10.1097/00002517-199506000-00013.
A 35-year-old patient who had progressive neck and shoulder pain and was neurologically intact was shown to have a C3 vertebral body osteolytic lesion. Open biopsy demonstrated an eosinophilic granuloma. The lesion was treated with external beam radiotherapy (1,000 cGy total dose). This case represents the thirteenth adult spinal eosinophilic granuloma reported in the literature. Spinal eosinophilic granuloma occurs more commonly in children. The characteristics of the 13 adult spinal eosinophilic cases reported suggest differences between the adult and childhood forms. Though rare, eosinophilic granuloma of the adult spine should be considered in the differential diagnosis of spinal osteolytic lesions.
一名35岁患者,有进行性颈部和肩部疼痛,神经系统检查正常,经检查发现有C3椎体溶骨性病变。开放活检显示为嗜酸性肉芽肿。该病变接受了外照射放疗(总剂量1000 cGy)。此病例是文献报道的第13例成人脊柱嗜酸性肉芽肿。脊柱嗜酸性肉芽肿在儿童中更常见。已报道的13例成人脊柱嗜酸性病例的特征表明成人和儿童形式之间存在差异。尽管罕见,但在脊柱溶骨性病变的鉴别诊断中应考虑成人脊柱嗜酸性肉芽肿。