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[临床实验室检查外部质量控制程序实际实施中的问题]

[Problems in practical implementation of the external quality control program in clinical laboratory investigations].

作者信息

Zaikin E V, Malakhov V N, Garanina E N, Delektorskaia L N

出版信息

Klin Lab Diagn. 1995 Jul-Aug(4):11-5.

PMID:7670810
Abstract

Center for External Quality Assessment in Laboratory Medicine has been organized in Russia. The National External Quality Assessment Scheme for 16 common analyses in clinical chemistry was implemented in 1992 under governmental support. A total of 1180 laboratories wished to participate in the program. 636 laboratories presented the results of analyses of 4 control serum pools, 2 with normal and 2 with increased concentrations of the constituents. Each control pool was analyzed twice allowing separate estimation of the accuracy and precision. Accuracy was assessed as the bias from method-dependent means and reference values. Reference methods were implemented for sodium, potassium, total protein, cholesterol, and triglycerides. Analysis of variance demonstrated that the errors are mainly due to the variability of methodologies in different laboratories, this variability being negligible.

摘要

俄罗斯已经组建了检验医学外部质量评估中心。1992年,在政府支持下实施了针对临床化学16项常见分析的国家外部质量评估计划。共有1180家实验室希望参与该项目。636家实验室提交了对4个对照血清库分析的结果,其中2个对照血清库的成分浓度正常,2个对照血清库的成分浓度升高。每个对照血清库都进行了两次分析,以便分别评估准确性和精密度。准确性通过与方法相关的均值和参考值之间的偏差来评估。钠、钾、总蛋白、胆固醇和甘油三酯采用参考方法进行分析。方差分析表明,误差主要是由于不同实验室方法的可变性导致的,这种可变性可以忽略不计。

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