Ferracini R, Bergmann M, Pileri S, Rigobello L, Azzolini U, Manetto V, Poggi S, Sabattini E, Frank G, Spagnolli F
Dept of Pathology, Bellaria Hospital, Bologna, Italy.
Clin Neuropathol. 1995 May-Jun;14(3):125-9.
A series of 6 patients with primary T-cell lymphomas of the central nervous system (PTCLCNS) is presented. The clinical, histological and immunohistological findings are shown. The lesions were infratentorial in the 34% and sopratentorial in the 66% of the cases. Of the 5 cases with an available follow-up only one died in the first year after diagnosis and one is alive and well after 42 months. These data agree with those of others series of PTCLCNS in the literature. In conclusion our data and those of the literature suggest that immunophenotyping should routinely be carried in primary non-Hodgkin's lymphomas of the CNS (PNHLCNS), because the T-cell forms run a more favourable course than the B-cell varieties.
本文报告了6例原发性中枢神经系统T细胞淋巴瘤（PTCLCNS）患者。展示了其临床、组织学和免疫组织学检查结果。34%的病例病变位于幕下，66%位于幕上。在5例有随访资料的患者中，仅1例在诊断后第1年死亡，1例在42个月后仍存活且状况良好。这些数据与文献中其他PTCLCNS系列的数据一致。总之，我们的数据和文献数据表明，对于中枢神经系统原发性非霍奇金淋巴瘤（PNHLCNS）应常规进行免疫表型分析，因为T细胞型的病程比B细胞型更为有利。
