Teuber G, Dienes H P, Meyer zum Büschenfelde K H, Gerken G
Department of Medicine I, Johannes Gutenberg Universität Mainz, Germany.
Hepatogastroenterology. 1995 Apr;42(2):189-91.
We report on a patient with chronic hepatitis C who developed acute hepatitis B during interferon alpha treatment. However, our patient promptly eliminated HBsAg and had a sustained complete response to interferon, even 6 months after the end of treatment. Acute hepatitis B superinfection in patients with chronic hepatitis C is a rarely observed event. The natural course of these patients is unknown. In our case it may be speculated that alpha-interferon treatment contributed to the prompt elimination of HBsAg from the serum.
我们报告了一名慢性丙型肝炎患者，该患者在接受α干扰素治疗期间发生了急性乙型肝炎。然而，我们的患者迅速清除了乙肝表面抗原（HBsAg），并且即使在治疗结束6个月后，对干扰素仍有持续的完全应答。慢性丙型肝炎患者发生急性乙型肝炎重叠感染是一种罕见的情况。这些患者的自然病程尚不清楚。在我们的病例中，可以推测α干扰素治疗有助于从血清中迅速清除HBsAg。
