偏头痛各亚型的患病率及性别比。

Prevalence and sex-ratio of the subtypes of migraine.

作者信息

Russell M B, Rasmussen B K, Thorvaldsen P, Olesen J

机构信息

Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark.

出版信息

Int J Epidemiol. 1995 Jun;24(3):612-8. doi: 10.1093/ije/24.3.612.

DOI:10.1093/ije/24.3.612

PMID:7672904

Abstract

BACKGROUND

The aim of this study was to provide the prevalence and sex-ratio of subtypes of migraine diagnosed by neurological interview according to the criteria of the International Headache Society.

METHODS

In all, 3000 males and 1000 females aged 40 years were randomly selected from the Danish population. They received a mailed questionnaire regarding migraine. The questionnaire response rate was 87%. People with self-reported migraine and a random sample of those reporting no migraine were invited to a headache interview, and a physical and a neurological examination. Those not reacting to the invitation were interviewed by telephone. Participation at the interview was 87%. Kappa was 0.77 validating self-reported migraine in the questionnaire against the diagnosis of the clinical interview.

RESULTS

Lifetime prevalences of migraine without aura, migraine with aura, migraine aura without headache, and migrainous disorder were 8%, 4%, 1% and 1% in males and 16%, 7%, 3% and 2% in females. Overall lifetime prevalence of any type of migraine was 18%; 12% in males and 24% in females. This is lower than the sum of the prevalences since migraine diagnoses are not mutually exclusive. The male:female ratios of migraine without aura, migraine with aura, migraine aura without headache, and migrainous disorder were approximately 1:2.

CONCLUSIONS

Migraine is more prevalent than previously thought. There was a significant preponderance in females of all the subtypes of migraine except migrainous disorder.

摘要

背景

本研究旨在根据国际头痛协会的标准，提供通过神经学访谈诊断的偏头痛亚型的患病率和性别比。

方法

从丹麦人群中随机选取3000名40岁男性和1000名40岁女性。他们收到了一份关于偏头痛的邮寄问卷。问卷回复率为87%。自我报告有偏头痛的人和随机抽取的无偏头痛报告者被邀请参加头痛访谈、体格检查和神经学检查。未对邀请做出回应的人通过电话进行访谈。访谈参与率为87%。kappa值为0.77，用于验证问卷中自我报告的偏头痛与临床访谈诊断结果的一致性。

结果

男性中无先兆偏头痛、有先兆偏头痛、无头痛的偏头痛先兆和偏头痛性疾病的终生患病率分别为8%、4%、1%和1%，女性分别为16%、7%、3%和2%。任何类型偏头痛的总体终生患病率为18%；男性为12%，女性为24%。这低于患病率总和，因为偏头痛诊断并非相互排斥。无先兆偏头痛、有先兆偏头痛、无头痛的偏头痛先兆和偏头痛性疾病的男女比例约为1:2。