Russell M B, Olesen J
Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark.
Cephalalgia. 1996 Oct;16(6):431-5. doi: 10.1046/j.1468-2982.1996.1606431.x.
Migrainous disorder was analysed in a large population-based study of 4000 forty-year-old males and females. All interviews were conducted by one physician and the diagnostic criteria of the International Headache Society were used. Of the 48 people with migrainous disorder, 40 had migrainous disorder without aura and 9 had migrainous disorder with aura. One person had co-occurrence of migrainous disorder with and without aura. The lifetime prevalence of migrainous disorder was 2.5% with a male:female ratio of 1:1.2. The first-degree relatives of probands with migrainous disorder were blindly interviewed. Compared with the general population, first-degree relatives of probands with migrainous disorder without aura had a slightly but less increased risk of migraine without aura than first-degree relatives of probands with migraine without aura. First-degree relatives of probands with migrainous disorder with aura had no increased risk of migraine with aura. We conclude that migrainous disorder without aura in some people is a type of migraine without aura and in other people not. Migrainous disorder with aura may be unrelated to migraine with aura.
在一项针对4000名40岁男性和女性的大型基于人群的研究中，对偏头痛性疾病进行了分析。所有访谈均由一名医生进行，并采用了国际头痛协会的诊断标准。在48例患有偏头痛性疾病的患者中，40例有无先兆偏头痛性疾病，9例有先兆偏头痛性疾病。1人同时患有有先兆和无先兆偏头痛性疾病。偏头痛性疾病的终生患病率为2.5%，男女比例为1:1.2。对患有偏头痛性疾病的先证者的一级亲属进行了盲法访谈。与普通人群相比，无先兆偏头痛性疾病先证者的一级亲属患无先兆偏头痛的风险略有增加，但低于有先兆偏头痛先证者的一级亲属。有先兆偏头痛性疾病先证者的一级亲属患先兆偏头痛的风险没有增加。我们得出结论，在一些人中，无先兆偏头痛性疾病是无先兆偏头痛的一种类型，而在另一些人中则不是。有先兆偏头痛性疾病可能与先兆偏头痛无关。
