Sellar R J
Department of Neuroradiology, Western General Hospital, Edinburgh, UK.
J Neurol Neurosurg Psychiatry. 1995 Sep;59(3):225-37. doi: 10.1136/jnnp.59.3.225.
Patients with transient ischaemic attacks or a non-disabling stroke who are surgical candidates should be screened with Doppler ultrasound, or MRA/CT, or both. The choice will depend on local expertise and availability. If DUS is used it is recommended that the equipment is regularly calibrated and a prospective audit of results, particularly of those patients that go on to angiography, is maintained locally. Those patients found to have the DUS equivalent of a 50% stenosis should have angiography only if surgical or balloon angioplasty treatment is contemplated. Angiography should be performed with meticulous technique to minimise risks. ANEURYSM AND ARTERIOVENOUS MALFORMATIONS: Angiography remains the investigation of choice for patients with subarachnoid haemorrhage. Magnetic resonance angiography and CT can demonstrate the larger aneurysm but because even small aneurysms can rupture with devastating effects, these techniques are not the examination of first choice. Angiography is also the only technique that adequately defines the neck of an aneurysm. This information is becoming increasingly important in management decisions-for instance, whether to clip or use a coil. Likewise angiography is the only technique to fully define the vascular anatomy of arteriovenous malformations although the size of the nidus can be monitored by MRA and this is a useful method of follow up after stereotactic radiosurgery, embolisation, or surgery. There are specific uses for MRA such as in patients presenting with a painful 3rd nerve palsy and as a screening test for those patients with a strong family history of aneurysms. VASCULITIS, FIBROMUSCULAR HYPERPLASIA, AND DISSECTION: These rare arterial diseases are best detected by angiography, although there are increasing reports of successful diagnosis by MRA. There are traps for the many unwary and MRA does not give an anatomical depiction of the arteries but a flow map. Slow flow may lead to signal loss and a false positive diagnosis of vasculitis.
对于拟行手术的短暂性脑缺血发作或非致残性卒中患者,应采用多普勒超声、磁共振血管造影(MRA)/计算机断层扫描血管造影(CT)或两者进行筛查。具体选择将取决于当地的专业技术水平和设备可用性。如果使用多普勒超声,建议定期校准设备,并在当地对结果进行前瞻性审核,尤其是对那些后续接受血管造影检查的患者。发现具有相当于50%狭窄程度的多普勒超声检查结果的患者,仅在考虑手术或球囊血管成形术治疗时才应进行血管造影。血管造影应采用精细技术进行,以尽量降低风险。
血管造影仍然是蛛网膜下腔出血患者的首选检查方法。磁共振血管造影和CT可以显示较大的动脉瘤,但由于即使是小动脉瘤破裂也可能产生毁灭性后果,因此这些技术并非首选检查方法。血管造影也是唯一能充分界定动脉瘤颈部的技术。这一信息在管理决策中变得越来越重要,例如决定是夹闭动脉瘤还是使用线圈栓塞。同样,血管造影是唯一能全面界定动静脉畸形血管解剖结构的技术,尽管畸形团的大小可通过磁共振血管造影进行监测,这是立体定向放射外科、栓塞或手术后随访的一种有用方法。磁共振血管造影有一些特定用途,例如用于出现疼痛性动眼神经麻痹的患者,以及作为有强烈动脉瘤家族史患者的筛查试验。
血管炎、纤维肌性增生和动脉夹层:这些罕见的动脉疾病最好通过血管造影进行检测,不过越来越多的报告显示磁共振血管造影也能成功诊断。对于许多粗心的人来说存在一些陷阱,而且磁共振血管造影并非给出动脉的解剖图像,而是血流图。血流缓慢可能导致信号丢失,从而对血管炎做出假阳性诊断。