Gillman G S, Parnes L S
Department of Otolaryngology, University of Western Ontario Faculty of Medicine, London.
J Otolaryngol. 1995 Jun;24(3):191-7.
The purpose of this investigation is to review the outcome of 83 consecutive acoustic neuroma patients, managed solely or in part by the Department of Otolaryngology at University Hospital, London, Ontario, over a 6-year period (1987 to 1993). The majority of patients underwent operative intervention, utilizing the middle cranial fossa, suboccipital, or most commonly, the translabyrinthine approach depending on the tumour size and level of residual hearing. Demographic, preoperative, intraoperative, and postoperative data are analyzed including complications of surgery. As well, we report on our experience with the use of fibrin glue in the dural closure following translabyrinthine resections and the resultant impact on the postoperative CSF leak rate. Overall, our results and complications are comparable to other large acoustic neuroma series in the literature. In addition, we feel that further study is merited in the use of fibrin glue in dural repair and its relationship to postoperative cerebrospinal fluid fistula.
本研究的目的是回顾安大略省伦敦市大学医院耳鼻喉科在1987年至1993年的6年期间单独或部分管理的83例连续听神经瘤患者的治疗结果。大多数患者接受了手术干预,根据肿瘤大小和残余听力水平,采用中颅窝、枕下或最常用的经迷路入路。分析了人口统计学、术前、术中和术后数据,包括手术并发症。此外,我们报告了在经迷路切除术后使用纤维蛋白胶进行硬脑膜闭合的经验以及对术后脑脊液漏发生率的影响。总体而言,我们的结果和并发症与文献中其他大型听神经瘤系列相当。此外,我们认为在硬脑膜修复中使用纤维蛋白胶及其与术后脑脊液瘘的关系值得进一步研究。