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[未来对临床试验有哪些期望?]

[What is expected of clinical tests in the future?].

作者信息

Hinohara S

机构信息

St. Luke's International Hospital, Tokyo.

出版信息

Rinsho Byori. 1995 Jul;43(7):639-43.

PMID:7674534
Abstract

I have described my interest in the field of clinical pathology since my undergraduate and graduate-training in Japan and also my concern about clinical pathology since my study in the United States of America. I have also presented a brief history of the Japanese Society of Clinical Pathology since it was organized in 1958. There are many laboratory tests which give some burden or invasive effects to the client. They have been done without paying much concern about the client and the quality of life of the client has not been widely considered. Although the secondary preventive medicine referred to as "the human dock" medical examination has widely spread throughout Japan in recent years, the primary preventive medicine, such as risk appraisal has not been strongly emphasized. In the future it must be considered more widely. Assessment of the laboratory data has been changing to put much emphasis on individual standard values. We must be very careful in evaluating the data of individual clients. This is very important when we deal with the elderly, whose diagnosis should be made with minimum laboratory studies. In the future clinical epidemiology and clinical decision analysis must be widely adapted in the field of practice of clinical pathology, so that the health care system will be efficiently working in all countries of the world.

摘要

自本科及在日本接受研究生培训以来,我就阐述了自己对临床病理学领域的兴趣,自赴美学习以来,我也表达了对临床病理学的关注。我还介绍了日本临床病理学会自1958年成立以来的简要历史。有许多实验室检查会给受检者带来一定负担或侵入性影响。这些检查在进行时并未充分考虑受检者,也未广泛考虑受检者的生活质量。尽管近年来被称为“人体健康检查”的二级预防医学在日本广泛普及,但诸如风险评估等一级预防医学却未得到大力强调。未来必须更广泛地加以考虑。实验室数据评估已转向更加重视个体标准值。我们在评估个体受检者的数据时必须非常谨慎。在处理老年人问题时这一点非常重要,对老年人的诊断应尽量减少实验室检查。未来,临床流行病学和临床决策分析必须在临床病理学实践领域广泛应用,以便全球各国的医疗保健系统都能高效运作。

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