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[白细胞闪烁扫描术:在炎症性疾病和骨髓疾病中的临床应用]

[Leukocyte scintigraphy: clinical application to inflammatory diseases and bone marrow diseases].

作者信息

Miyazaki C

机构信息

Department of Diagnostic Radiology, Sapporo City General Hospital.

出版信息

Kaku Igaku. 1995 Jul;32(7):703-7.

PMID:7674583
Abstract

111In or 99mTc-HMPAO labeled leukocyte scintigraphy has been shown to be useful in detection and diagnosis of infections and inflammatory lesions. Results from multiple retrospective series indicate that leukocyte scintigraphy achieves sensitivity and specificity of near 90% in abdominal abscess detection. 99mTc-HMPAO labeled leukocyte scintigraphy is now an accepted technique in the assessment of patients with inflammatory bowel disease and the diagnostic value of early 99mTc-HMPAO labeled leukocyte images has been discussed. It is known that 99mTc-HMPAO labeled leukocytes migrate to a large extent to the bone marrow. 99mTc-HMPAO labeled leukocytes may prove to be a practical agent for bone marrow imaging. In this report, definition, classification and pathological consideration of inflammation, and history, diagnostic efficacy and consideration for clinical application of inflammation scintigraphy are reviewed.

摘要

已证明¹¹¹In或⁹⁹ᵐTc-HMPAO标记的白细胞闪烁扫描术在感染和炎症性病变的检测与诊断中很有用。多个回顾性系列研究的结果表明,白细胞闪烁扫描术在腹部脓肿检测中实现了近90%的敏感性和特异性。⁹⁹ᵐTc-HMPAO标记的白细胞闪烁扫描术现在是评估炎症性肠病患者的一种公认技术,并且已经讨论了早期⁹⁹ᵐTc-HMPAO标记的白细胞图像的诊断价值。众所周知,⁹⁹ᵐTc-HMPAO标记的白细胞在很大程度上迁移到骨髓。⁹⁹ᵐTc-HMPAO标记的白细胞可能被证明是一种用于骨髓成像的实用剂。在本报告中,对炎症的定义、分类和病理考量,以及炎症闪烁扫描术的历史、诊断效能和临床应用考量进行了综述。

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Kaku Igaku. 1995 Jul;32(7):703-7.
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