Bevers R F, Bakker D J, Kurth K H
Academic Medical Center, University of Amsterdam, The Netherlands.
Lancet. 1995 Sep 23;346(8978):803-5. doi: 10.1016/s0140-6736(95)91620-2.
Radiation-induced severe haemorrhagic cystitis is difficult to treat. Conventional treatments may decrease haematuria but do not affect the radiocystitis itself. Hyperbaric oxygen treatment has been reported to do both. We report the results of a prospective study of hyperbaric oxygen (20 sessions of 100% oxygen inhalation at 3 bar for 90 min in a multiplace hyperbaric chamber) to 40 patients with biopsy-proven radiation cystitis and severe haematuria. Haematuria disappeared completely or improved in 37 patients after treatment. Mean follow-up was 23.1 months (range 1-74); and the recurrence rate was 0.12/year. There were no adverse effects. Hyperbaric oxygen treatment should be considered for patients with severe radiation-induced haematuria.
放射性诱发的严重出血性膀胱炎难以治疗。传统治疗方法可能会减少血尿，但对放射性膀胱炎本身并无作用。据报道，高压氧治疗对两者均有效果。我们报告了一项对40例经活检证实患有放射性膀胱炎且有严重血尿的患者进行高压氧治疗（在多人高压氧舱中，以3巴的压力吸入100%氧气，每次90分钟，共进行20次治疗）的前瞻性研究结果。治疗后，37例患者的血尿完全消失或有所改善。平均随访时间为23.1个月（范围1 - 74个月）；复发率为每年0.12次。未出现不良反应。对于患有严重放射性诱发血尿的患者，应考虑采用高压氧治疗。
