Bonoli P, Grillone G, Fossa S, Franceschelli N, Lari S, Leykin Y, Nastasi M, Zanoni A
Servizio di Anestesia e Rianimazione, Istituti Ortopedici Rizzoli, Bologna.
Minerva Anestesiol. 1995 Apr;61(4):115-25.
This study was designed to asses in a prospective survey the intra and post-operative adverse outcome of paediatric patients in Italy. The data was carried out in representative samples of anaesthetics performed in different Italian Institutions, which were chosen by the National Study Group for Paediatric Anaesthesia, and included: paediatric, general, specialistic hospitals and departments. A total of 9289 anaesthetics were collected and studied. The mean age of the patients was 62.5 months. In the 320 cases (3.4%) 299 minor (3.2%) and 21 major (0.2%) complications occurred during or within 24 hours of surgery and anaesthesia. Seven of the major complications resulted in the exitus of the patients (0.07%). Fifty percent of the accidents regarded respiratory and twenty percent cardiovascular systems. The major incidence (risk factors) of the minor complications was present in patients less than 6 months, ASA group 2-3-4, emergency surgery, patients with associated pathology, long duration of anaesthesia and high risk operations. The incidence of the major complications appears closely related to: patients age and clinical assessment, weight, ASA group, kind of the operation, indications and durations of the surgery, while in the exitus group the major risk factor is the preoperative pathology, surgical procedures, and then: age, weight, ASA and finally surgery.
本研究旨在通过一项前瞻性调查评估意大利儿科患者的术中及术后不良结局。数据来自意大利不同机构实施麻醉的代表性样本，这些机构由国家儿科麻醉研究小组选取，包括儿科、综合、专科医院及科室。共收集并研究了9289例麻醉病例。患者的平均年龄为62.5个月。在320例病例（3.4%）中，299例发生轻微并发症（3.2%），21例发生严重并发症（0.2%），这些并发症发生在手术及麻醉期间或24小时内。7例严重并发症导致患者死亡（0.07%）。50%的不良事件涉及呼吸系统，20%涉及心血管系统。轻微并发症的主要发生率（风险因素）存在于6个月以下的患者、ASA 2-3-4级患者、急诊手术患者、伴有相关病症的患者、麻醉时间长及高风险手术患者中。严重并发症的发生率似乎与患者年龄及临床评估、体重、ASA分级、手术类型、手术指征及时长密切相关，而在死亡组中，主要风险因素是术前病症、手术操作，其次是年龄、体重、ASA分级，最后是手术。
