Jensen K E
Dansk Videncenter for Magnetisk Resonans og røntgenafdelingen, Hvidovre Hospital, København.
Ugeskr Laeger. 1995 Aug 28;157(35):4802-8.
Magnetic resonance imaging (MRI) is a highly sensitive alternative to plain radiography, CT, and radionuclide studies for the imaging of normal and abnormal bone marrow. The cellularity and the corresponding fat/water ratio within the bone marrow show clear changes in haematological diseases. This enables MRI to detect differences between fatty, fibrotic, aplastic and hypercellular marrow in patients with haematological disease. MRI can evaluate the distribution of bone marrow disease because it has the potential for visualization of almost the entire bone marrow compartment. However, MRI is unable to establish the primary diagnosis in haematological bone marrow disease with diffuse hypercellular marrow. In case of insufficient biopsy, MRI can provide important differential diagnostic information as well as guidance for further biopsy attempts. MRI is a useful complement to morphological bone marrow evaluation in malignancies with focal marrow involvement, such as malignant lymphoma or metastases.
磁共振成像(MRI)是一种对正常和异常骨髓成像的高度敏感的检查方法,可替代X线平片、CT和放射性核素检查。骨髓内的细胞成分以及相应的脂肪/水比例在血液系统疾病中会出现明显变化。这使得MRI能够检测血液系统疾病患者脂肪性、纤维化、再生障碍性和细胞增多性骨髓之间的差异。MRI可以评估骨髓疾病的分布情况,因为它几乎能够显示整个骨髓腔。然而,MRI无法对弥漫性细胞增多性骨髓的血液系统骨髓疾病做出初步诊断。在活检不足的情况下,MRI可以提供重要的鉴别诊断信息,并为进一步的活检尝试提供指导。对于有局灶性骨髓受累的恶性肿瘤,如恶性淋巴瘤或转移瘤,MRI是对形态学骨髓评估的有用补充。