Kuon E, Pfahlbusch K, Lang E
Medizinische Klinik des Waldkrankenhauses St. Marien Abteilung Kardiologie, Erlangen.
Z Kardiol. 1995 Jul;84(7):512-9.
Though the predictive value of a diagonal earlobe crease (ELC) concerning coronary heart disease (CHD) is assessed controversially and seems to be influenced by age and ethnic origin, the ELC is mainly regarded as a reliable and valid sign of CHD. 670 patients, the greatest collective so far undergoing coronary angiography, were investigated prospectively with respect to the correlation between ELC and a hemodynamically relevant CHD (coronary diameter stenosis > 70%). In presence of ELC, CHD was observed in 55.0%, in its absence in 55.9% (One-vessel-disease (1-VD) 25.8% vs 26.7%, 2-VD 14.5% vs 14.4%, > 2-VD 14.8% vs 14.8%; n.s.). ELC itself was dependent on age (p < 0.000009), overweight (body mass index (BMI) > 25 kg/m2, p < 0.034) and hyperuricemia (> 7.0 mg%; p < 0.05), but not influenced by sex and other coronary risk factors such as smoking, diabetes, hypercholesterinemia and hyperlipoidemia, physical in-activity and family history of CHD. Actual just as former smoking and male sex are associated positively to CHD, whereas diabetes, hypercholesterinemia and hyperlipoidemia seem to predict a two-or multivessel disease: this emphasizes the validity of our data.
The ear-lobe crease is associated with age and overweight, but does not predict a hemodynamically relevant coronary heart disease.
尽管关于耳垂斜纹(ELC)对冠心病(CHD)的预测价值存在争议,且似乎受年龄和种族影响,但ELC主要被视为CHD的一个可靠且有效的体征。对670例患者(这是迄今为止接受冠状动脉造影的最大样本群体)进行了前瞻性研究,以探讨ELC与血流动力学相关的CHD(冠状动脉直径狭窄>70%)之间的相关性。存在ELC时,CHD的发生率为55.0%,不存在ELC时为55.9%(单支血管病变(1-VD)为25.8%对26.7%,2支血管病变为14.5%对14.4%,>2支血管病变为14.8%对14.8%;无显著差异)。ELC本身取决于年龄(p<0.000009)、超重(体重指数(BMI)>25kg/m²,p<0.034)和高尿酸血症(>7.0mg%;p<0.05),但不受性别以及其他冠心病危险因素如吸烟、糖尿病、高胆固醇血症和高脂血症、缺乏体育活动和冠心病家族史的影响。当前吸烟和男性性别与CHD呈正相关,而糖尿病、高胆固醇血症和高脂血症似乎预示着双支或多支血管病变:这强调了我们数据的有效性。
耳垂斜纹与年龄和超重有关,但不能预测血流动力学相关的冠心病。