Motamed M, Pelekoudas N
Department of Otolaryngology, Royal Free Hospital, London, UK.
Int J Clin Pract. 1998 Jul-Aug;52(5):305-6.
Studies on selected cardiac patients have supported the association between diagonal ear-lobe crease (ELC) sign and coronary artery disease (CAD). The aim of this study was to assess the value of this sign as a predictor of the presence of CAD in the non-cardiac patient population, to see if any association exists between the two and to compare any association with other established risk factors. A significant association exists between ELC and a history of CAD, which is not solely attributable to the increased prevalence of the sign with increasing age. A higher correlation was found between CAD and ELC than between CAD and other risk factors. The sensitivity of the sign was 48%, the specificity 88%, and the positive predictive value 16%. In this population the finding of an ELC is of little clinical value.
对部分心脏病患者的研究支持了耳垂斜线纹（ELC）体征与冠状动脉疾病（CAD）之间的关联。本研究的目的是评估该体征作为非心脏病患者群体中CAD存在的预测指标的价值，观察两者之间是否存在关联，并将该关联与其他已确定的风险因素进行比较。ELC与CAD病史之间存在显著关联，这并非仅仅归因于该体征随年龄增长而患病率增加。发现CAD与ELC之间的相关性高于CAD与其他风险因素之间的相关性。该体征的敏感性为48%，特异性为88%，阳性预测值为16%。在这一人群中，发现ELC几乎没有临床价值。
