Lamot Sebastián B, Lonegro Gustavo G, Hernández Marcos, Lamot Juan M, Lapresa Susana, Sobrino Edgardo
Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Medicina (B Aires). 2007;67(4):321-5.
The diagonal earlobe crease is a sign theorically related to coronary artery disease. The purpose of this study was to prove the usefulness of this sign. A total of 104 patients were examined (ages 30 to 80) grouped by age and sex. Forty nine of them were diagnosed of having coronary artery disease by coronary angiography (a 70% obstruction of one of the major arteries), and/or myocardial perfusion imaging with Thallium 201 (fixed defects). The control group included 55 patients (asymptomatic with normal electrocardiogram). Data here obtained included sensitivity (61.2%), specificity (78 2%), positive predictive value (71.4%) and negative predictive value (69.3%). We found a significant relation between the presence of the diagonal earlobe crease and coronary artery disease. We consider it a sign that could prove useful in clinical practice, mainly among patients aged between 30 and 60.
耳垂斜线皱纹是一种理论上与冠状动脉疾病相关的体征。本研究的目的是证实这一体征的实用性。共检查了104例患者(年龄30至80岁),按年龄和性别分组。其中49例通过冠状动脉造影(主要动脉之一阻塞70%)和/或用铊201进行心肌灌注显像(固定缺损)被诊断患有冠状动脉疾病。对照组包括55例患者(无症状,心电图正常)。这里获得的数据包括敏感性(61.2%)、特异性(78.2%)、阳性预测值(71.4%)和阴性预测值(69.3%)。我们发现耳垂斜线皱纹的出现与冠状动脉疾病之间存在显著关联。我们认为它是一种在临床实践中可能有用的体征,主要适用于年龄在30至60岁之间的患者。