Sternlo J E, Hybbinette C H
Department of Anaesthesia, Kalmar County Hospital, Sweden.
Acta Anaesthesiol Scand. 1995 May;39(4):557-9. doi: 10.1111/j.1399-6576.1995.tb04119.x.
Despite the extensive use of low molecular weight heparins (LMWH) for thromboprophylaxis, only two serious complications have thus far been reported where spinal haematomas were incurred after epidural and spinal blocks in patients on such treatment. In our patient, who was on thromboprophylaxis with the LMWH drug enoxaparin, catheter epidural anaesthesia was abandoned due to a bloody tap and superseded by spinal anaesthesia. More than 40 hours later she had developed a paraparesis and complete sensory loss in the lower extremities. The MRT image showed haematomas epi- and subdurally, as well as subarachnoidally, but no epidural bleeding was seen at laminectomy.
尽管低分子量肝素(LMWH)广泛用于血栓预防,但迄今为止仅报告了两例严重并发症,即接受此类治疗的患者在硬膜外和脊髓阻滞术后发生脊髓血肿。在我们的患者中,其正在使用LMWH药物依诺肝素进行血栓预防,因穿刺抽出血液而放弃了导管硬膜外麻醉,改用脊髓麻醉。40多个小时后,她出现了双下肢轻瘫和完全性感觉丧失。磁共振成像(MRT)显示硬膜外、硬膜下以及蛛网膜下均有血肿,但在椎板切除术中未发现硬膜外出血。