Nakamura E, Mizuta H, Takagi K
Department of Orthopedic Surgery, Kumamoto University School of Medicine, Japan.
Acta Orthop Scand. 1995 Aug;66(4):313-6. doi: 10.3109/17453679508995551.
We investigated the effects of tibial lengthening by callotasis on the knee articular cartilage in 10 rabbits at 3 and 6 months after distraction. The distraction rate was 1 mm per day, until a 30 percent gain in length. On the right tibia, the daily distraction frequency was in 2 steps by hand, while on the left it was in 120 steps by an autodistractor. 5 animals were killed at 3 months and 5 at 6 months following distraction, and their knee joints were radiographically and histologically examined. On the 2-step side, arthrotic changes at 3 and 6 months after distraction were found in 3 of 5 and 4 of 5 knees, respectively. The severity of change increased with time. On the 120-step side, however, no arthrotic changes were found, except in one knee at 6 months. Our findings suggest that by increasing the frequency of distraction for limb lengthening one can prevent the onset of arthrosis in adjacent joints.
我们研究了在10只兔子身上进行骨痂延长术胫骨延长后3个月和6个月时对膝关节软骨的影响。牵张速率为每天1毫米，直至长度增加30%。右侧胫骨通过手动分两步进行每日牵张，而左侧通过自动牵张器分120步进行。牵张后3个月处死5只动物，6个月处死5只动物，并对其膝关节进行放射学和组织学检查。在分两步牵张的一侧，牵张后3个月和6个月时，分别在5个膝关节中的3个和4个发现了关节变化。变化的严重程度随时间增加。然而，在分120步牵张的一侧，除了6个月时的一个膝关节外，未发现关节变化。我们的研究结果表明，通过增加肢体延长牵张的频率，可以预防相邻关节的关节病发作。
