人GRF(1 - 29)NH2引起大鼠胸膜和腹膜肥大细胞组胺释放。
Histamine release on rat pleural and peritoneal mast cells elicited by human GRF(1-29)NH2.
作者信息
Estévez M D, Botana M A, Arnáez E, Vieytes M R, Botana L M
机构信息
Department of Pharmacology, Faculty of Veterinary Medicine, Lugo, Spain.
出版信息
Int Arch Allergy Immunol. 1993;100(1):86-8. doi: 10.1159/000236392.
PMID:7679022
Abstract
We have studied the release of histamine elicited by human GRF(1-29)NH2 on rat peritoneal and pleural mast cells. The secretion is temperature dependent, the release being optimal at 37 degrees C, and it can be inhibited with antimycin A. The activation of pleural and peritoneal mast cells is similar, but there is a slight inhibition for both populations after purification with Percoll.
摘要
我们研究了人促生长激素释放因子（GRF）（1-29）NH₂对大鼠腹膜和胸膜肥大细胞组胺释放的影响。这种分泌依赖于温度，在37℃时释放最为理想，并且可以被抗霉素A抑制。胸膜和腹膜肥大细胞的激活情况相似，但在用 Percoll 纯化后，这两种细胞群体都有轻微的抑制。
Zotero 插件