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A study of the genetic polymorphism of human inter-alpha-trypsin-inhibitor (ITI) in the Han population, Chengdu, China.

作者信息

Hou Y, Gou Q, Wu M

机构信息

Department of Forensic Serology, West China University of Medical Sciences, Chengdu, Sichuan.

出版信息

Hum Genet. 1993 Feb;90(6):661-2.

PMID:7680331
Abstract

Phenotypes of inter-alpha-trypsin-inhibitor (ITI) have been determined by isoelectric focusing on polyacrylamide gels followed by immunofixation. The phenotype frequencies of ITI in the Han population in Chengdu, P.R. China have been investigated using this method. In addition, family studies have been conducted in 21 families. The results show that ITI is polymorphic in the Han population in Chengdu, China. The allele frequencies are as follows: ITI1 = 0.5763. ITI2 = 0.4107, ITI*3 = 0.0130. ITI is thus a new and promising genetic marker that can be used in the field of forensic haematogenetics.

摘要

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引用本文的文献

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Inter-alpha-trypsin inhibitor polymorphism. An improved phenotyping procedure and two new alleles.
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本文引用的文献

1
Genetic polymorphism of inter-alpha-trypsin-inhibitor (ITI): formal genetic and linkage analyses.
Hum Genet. 1991 May;87(1):89-90. doi: 10.1007/BF01213100.
2
A "new" genetic polymorphism of a human serum protein: inter-alpha-trypsin-inhibitor.
Hum Genet. 1990 Jan;84(2):151-4. doi: 10.1007/BF00208930.
3
The inter-alpha-trypsin inhibitor.α-胰蛋白酶抑制因子间体
Methods Enzymol. 1976;45:760-72. doi: 10.1016/s0076-6879(76)45069-3.