临床应用中的生长调节素-1（胰岛素样生长因子-I）。事实与潜力。 - Suppr

Somatomedin-1 (insulin-like growth factor-I) in clinical use. Facts and potential.

作者信息

Laron Z

机构信息

Institute of Pediatric and Adolescent Endocrinology, Children's Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tiqva, Israel.

出版信息

Drugs. 1993 Jan;45(1):1-8. doi: 10.2165/00003495-199345010-00001.

DOI:10.2165/00003495-199345010-00001

PMID:7680980

Abstract

摘要

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Somatomedin-1 (insulin-like growth factor-I) in clinical use. Facts and potential.临床应用中的生长调节素-1（胰岛素样生长因子-I）。事实与潜力。

Drugs. 1993 Jan;45(1):1-8. doi: 10.2165/00003495-199345010-00001.

Acute response to recombinant insulin-like growth factor I in a patient with Mendenhall's syndrome.

N Engl J Med. 1990 Nov 15;323(20):1425-6. doi: 10.1056/NEJM199011153232016.

Therapeutic potential of rhIGF-I in diabetes and conditions of insulin resistance.

J Intern Med. 1993 Dec;234(6):561-70. doi: 10.1111/j.1365-2796.1993.tb01014.x.

Insulin-like growth factor-I treatment of growth disorders, diabetes mellitus and insulin resistance.胰岛素样生长因子-I治疗生长障碍、糖尿病和胰岛素抵抗。

Trends Endocrinol Metab. 2005 May-Jun;16(4):190-7. doi: 10.1016/j.tem.2005.03.011.

Metabolic effects of insulin-like growth factor I with special reference to diabetes.

Acta Paediatr Suppl. 1994 Apr;399:165-70. doi: 10.1111/j.1651-2227.1994.tb13317.x.

[Human insulin-like growth factor I and treatment in diabetes].[人胰岛素样生长因子I与糖尿病治疗]

Duodecim. 1994;110(23-24):2197-201.

Metabolic effects of insulin-like growth factor-I: a focus on insulin sensitivity.

Metabolism. 1995 Oct;44(10 Suppl 4):108-12. doi: 10.1016/0026-0495(95)90230-9.

Insulin-like growth factor-1 therapy in diabetes: physiologic basis, clinical benefits, and risks.胰岛素样生长因子-1治疗糖尿病：生理基础、临床益处及风险。

Ann Intern Med. 1994 Jan 1;120(1):47-55. doi: 10.7326/0003-4819-120-1-199401010-00009.

Insulin-like growth factor I therapy for diabetes mellitus?

Diabetes Care. 1994 Jan;17(1):92-6. doi: 10.2337/diacare.17.1.92.

Clinical uses of insulin-like growth factor I.胰岛素样生长因子I的临床应用。

Adv Endocrinol Metab. 1995;6:143-65.

引用本文的文献

Clinical use of somatomedin-1: yes or no?生长调节素-1的临床应用：是或否？

Paediatr Drugs. 1999 Jul-Sep;1(3):155-9. doi: 10.2165/00128072-199901030-00001.

Growth hormone secretagogues. Clinical experience and therapeutic potential.生长激素促分泌素。临床经验与治疗潜力。

Drugs. 1995 Oct;50(4):595-601. doi: 10.2165/00003495-199550040-00002.

本文引用的文献

Therapeutic potential of insulinlike growth factor i.胰岛素样生长因子 i 的治疗潜力。

Trends Endocrinol Metab. 1990 May-Jun;1(5):254-60. doi: 10.1016/1043-2760(90)90006-o.

Tumor of the pineal body with high insulin resistance.

J Indiana State Med Assoc. 1950 Jan;43(1):32-6, illust.

Puberty in Laron type dwarfism.

Eur J Pediatr. 1980 Jun;134(1):79-83. doi: 10.1007/BF00442408.

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action.生长调节素C的组织浓度：合成多部位及旁分泌或自分泌作用机制的进一步证据

Proc Natl Acad Sci U S A. 1984 Feb;81(3):935-9. doi: 10.1073/pnas.81.3.935.

Insulin-like growth factor I/somatomedin C (IGF-I/Sm C): comparison of natural, solid phase synthetic and recombinant DNA analog peptides in two radioligand assays.胰岛素样生长因子I/生长调节素C（IGF-I/Sm C）：在两种放射性配体分析中天然、固相合成及重组DNA类似肽的比较

Endocrinology. 1984 Dec;115(6):2490-2. doi: 10.1210/endo-115-6-2490.

Somatomedin activity in disorders of nutrition and metabolism.

Clin Endocrinol Metab. 1984 Mar;13(1):145-89. doi: 10.1016/s0300-595x(84)80012-2.

Deficiencies of growth hormone and somatomedins in man.

Spec Top Endocrinol Metab. 1983;5:149-99.

Defect of human growth hormone receptors in the liver of two patients with Laron-type dwarfism.两名拉伦氏侏儒症患者肝脏中人类生长激素受体的缺陷。

Isr J Med Sci. 1984 Jan;20(1):8-11.

Laron-type dwarfism (hereditary somatomedin deficiency): a review.

Ergeb Inn Med Kinderheilkd. 1984;51:117-50. doi: 10.1007/978-3-642-69070-9_3.

Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: dependence on growth hormone status.灌注大鼠肝脏中胰岛素样生长因子及其结合蛋白的合成与分泌：对生长激素状态的依赖性。

Endocrinology. 1983 Jul;113(1):297-305. doi: 10.1210/endo-113-1-297.

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Somatomedin-1 (insulin-like growth factor-I) in clinical use. Facts and potential.

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