Karwan R
Institute of Tumor Biology, University of Vienna, Austria.
FEBS Lett. 1993 Mar 15;319(1-2):1-4. doi: 10.1016/0014-5793(93)80025-p.
RNase P and RNase MRP are related ribonucleoproteins. RNase MRP processes mitochondrial precursor- (primer) RNAs, whereas RNase P cleaves precursor-tRNAs to produce their mature 5'-ends. Both RNase P and RNase MRP are associated with the Th/To ribonucleoprotein suggesting possible interrelated pathways and/or functions. All known RNase P and RNase MRP RNAs contain conserved structural elements possibly involved in catalysis/substrate binding, but these elements do not predict all cellular functions of the RNPs.
核糖核酸酶P（RNase P）和线粒体RNA加工核糖核酸酶（RNase MRP）是相关的核糖核蛋白。RNase MRP加工线粒体前体（引物）RNA，而RNase P切割前体tRNA以产生其成熟的5'末端。RNase P和RNase MRP都与Th/To核糖核蛋白相关，提示可能存在相互关联的途径和/或功能。所有已知的RNase P和RNase MRP RNA都含有可能参与催化/底物结合的保守结构元件，但这些元件并不能预测核糖核蛋白的所有细胞功能。
