静脉溃疡的“陷阱”假说。
The "trap" hypothesis of venous ulceration.
作者信息
Falanga V, Eaglstein W H
机构信息
University of Miami School of Medicine, Department of Dermatology and Cutaneous Surgery, Florida 33101.
出版信息
Lancet. 1993 Apr 17;341(8851):1006-8. doi: 10.1016/0140-6736(93)91085-z.
PMID:7682272
Abstract
The pathogenesis of venous ulceration is unknown. We propose that macromolecules leaking into the dermis as a result of venous hypertension bind to or "trap" growth factors and matrix material, which then become unavailable for tissue repair and for the maintenance of tissue integrity.
摘要
静脉溃疡的发病机制尚不清楚。我们提出，由于静脉高压导致大分子渗入真皮，这些大分子会与生长因子和基质材料结合或“捕获”它们，从而使组织修复和维持组织完整性所需的这些物质无法发挥作用。
Zotero 插件