Demaerel P, Kingsley D P, Kendall B E
Department of Neuroradiology, Hospital for Sick Children, London, UK.
Pediatr Radiol. 1993;23(1):29-33. doi: 10.1007/BF02020217.
CT findings on 170 patients presenting with isolated moderate to severe neurodevelopmental delay have been compared with the final diagnosis. MRI was undertaken in 29 patients. Eighty per cent of the patients remained undiagnosed, and although the MRI findings were abnormal in 65.5% compared with only 30% of the CT examinations, imaging uncommonly suggested a specific diagnosis. Biochemical and chromosomal investigations were significantly more diagnostic. The results of these studies should restrict the number of non-contributory neuroradiological examinations. The superior intrinsic contrast of MRI will detect more lesions, particularly in white matter, but these are rarely diagnostic and where access to MRI is limited, CT is usually adequate.
对170例单纯性中度至重度神经发育迟缓患者的CT检查结果与最终诊断结果进行了比较。29例患者进行了MRI检查。80%的患者仍未确诊，尽管MRI检查结果异常的比例为65.5%，而CT检查仅为30%，但影像学检查很少能提示明确的诊断。生化和染色体检查的诊断价值明显更高。这些研究结果应限制无诊断价值的神经放射学检查的数量。MRI更好的内在对比度能检测到更多病变，尤其是白质病变，但这些病变很少能确诊，而且在MRI检查受限的情况下，CT通常就足够了。
