Lingam S, Read S, Holland I M, Wilson J, Brett E M, Hoare R D
Arch Dis Child. 1982 May;57(5):381-3. doi: 10.1136/adc.57.5.381.
Seventy-six children had computerized tomography scans as part of an investigation of mental subnormality; most of them are severely retarded and all those over age 5 years attend special schools. Seventy-two per cent of the children had normal scans. Twenty per cent showed cerebral atrophy and in only 8% was there a specific abnormality (agenesis of corpus callosum, arachnoid cyst, communicating hydrocephalus). None of these findings had any positive prognostic implication. Sedation or general anaesthesia was required for all except one child. Injection pethidine compound was used for children under age 5 years or less than 30 kg in weight, and trimeprazine orally was used for older children. The radiation exposure was high--5.6 rad per scan, which is 100 times greater than that from a posteroanterior and lateral chest x-ray film. For these reasons computerised tomography scans cannot be recommended as a routine part of the investigation of children with non-specific mental subnormality.
76名儿童接受了计算机断层扫描，作为智力发育迟缓调查的一部分；他们中的大多数严重智障，所有5岁以上的儿童都就读于特殊学校。72%的儿童扫描结果正常。20%显示脑萎缩，只有8%存在特定异常（胼胝体发育不全、蛛网膜囊肿、交通性脑积水）。这些发现均无任何积极的预后意义。除一名儿童外，所有儿童均需要镇静或全身麻醉。5岁以下或体重不足30公斤的儿童使用注射用复方哌替啶，年龄较大的儿童口服异丁嗪。辐射暴露量很高——每次扫描5.6拉德，这比后前位和侧位胸部X光片的辐射量高100倍。由于这些原因，计算机断层扫描不能作为非特异性智力发育迟缓儿童调查的常规部分被推荐。
