Gutin A M, Galzitskaia O V
Biofizika. 1993 Jan-Feb;38(1):93-8.
A simple model of secondary structure of large native RNAs is proposed which makes allowance for the formation of week non-specific helices in addition to the formation of strong helices. It is shown that in this model, the same as in the one investigated earlier [1], cooperative melting of helices formed by interactions between remote parts of chain by the mechanism of the second order phase transition is observed upon changing the stability of helices.
提出了一个大型天然RNA二级结构的简单模型,该模型除了考虑强螺旋的形成外,还考虑了弱非特异性螺旋的形成。结果表明,在该模型中,与之前研究的模型[1]一样,当改变螺旋的稳定性时,会观察到由链的远端部分之间通过二级相变机制相互作用形成的螺旋的协同解链。