苏氨酸合成酶基因（thrS）翻译调控元件与二聚体苏氨酰转运RNA合成酶之间的对称相互作用。
Symmetrical interactions between the translational operator of the thrS gene and dimeric threonyl transfer RNA synthetase.
作者信息
Bedouelle H
机构信息
Groupe d'Ingénierie des Protéines (CNRS URA 1129), Unité de Biochimie Cellulaire, Institut Pasteur, Paris, France.
出版信息
J Mol Biol. 1993 Apr 5;230(3):704-8. doi: 10.1006/jmbi.1993.1190.
Threonyl-tRNA synthetase from Escherichia coli represses the translation of its coding gene, thrS, by binding an operator located in the leader region of its messenger RNA. Published data on the structure of this leader region and on its interaction with threonyl-tRNA synthetase support a model in which each of two stem-and-loop structures mimics the anticodon arm of tRNA(Thr) and binds a different subunit of one synthetase dimer.
来自大肠杆菌的苏氨酰 - tRNA合成酶通过结合位于其信使RNA前导区的一个操纵子来抑制其编码基因thrS的翻译。关于该前导区结构及其与苏氨酰 - tRNA合成酶相互作用的已发表数据支持这样一种模型，即两个茎环结构中的每一个都模拟tRNA(Thr)的反密码子臂，并结合一个合成酶二聚体的不同亚基。
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