Kautzky M, Susani M, Steurer M, Höfler H
II. Univ.-Klinik für Hals-Nasen-Ohrenkrankheiten, Universität Wien.
Laryngorhinootologie. 1993 Apr;72(4):181-6. doi: 10.1055/s-2007-997881.
A pulsed Holmium:YAG-laser (lambda = 2,120 nm) was used for the first time clinically in tumour surgery. The primary lesion of a transitional cell carcinoma of the nasopharynx with metastatic disease in the neck (T2N2Mo) was laser resected in a photoablative manner with a minor thermal component without danger of damage to the skull base. Neck dissection was performed by conventional surgery. In comparison to laser types depending primarily on the thermal effects of laser-tissue interaction the coagulative necrosis zone following Holmium:YAG-laser surgery is small and there is no area of carbonisation. Macroscopic wound healing showed no complications and was completed after three weeks. At this time radiation therapy was started. The results of the histological examination and the physical properties of this new infrared laser system are discussed as well as the possibilities of flexible fiber Holmium:YAG endoscopic laser tumour surgery in clinical use.
钇铝石榴石激光（波长 = 2120 纳米）首次在肿瘤手术中临床应用。对一名患有颈部转移疾病的鼻咽癌移行细胞癌（T2N2M0）的原发灶进行了激光切除，采用光消融方式，热成分较小，无损伤颅底的危险。颈部清扫术通过传统手术进行。与主要依赖激光 - 组织相互作用热效应的激光类型相比，钬：钇铝石榴石激光手术后的凝固性坏死区较小，且无碳化区域。宏观伤口愈合无并发症，三周后完成。此时开始进行放射治疗。讨论了这种新型红外激光系统的组织学检查结果和物理特性，以及柔性光纤钬：钇铝石榴石内镜激光肿瘤手术在临床应用中的可能性。
